...The Proactive Worm Containment (PWC) approach developed by the researchers is supposed to augment traditional signature-based worm and virus detection, as well as so-called rate-limiting technology. The researchers have applied for a provisional patent for PWC, which uses anomaly detection, not signatures. It looks at packet rate, frequency of connections, and the diversity of connections, and it can find and detain a worm within milliseconds of a cyber attack...The idea is for the PWC to be included as an add-on in AV products or firewalls...
The researchers put together a .pdf for download but that link is not working. You can view the same information as HTML at this link.
Related article: Penn State researchers invent anti-worm technology.