There is a small utility that I use when faced with your type of problem; what it does is add a command in the mouse-RIGHT click shell menu, Take Ownership. This gives you what is called "ownership" of any file or folder that is on your drive. I have used the Window 7 version for years. Although I have never used the W10 version, it comes from the same author so I assume that it will work for you also.
> Go Here and download Take Ownership from the number 2 header. Save to your desktop.
> Double-click on the file to install. You may be prompted, click/tap on Run, Yes (UAC), Yes, and OK to approve the merge (from the website instructions).
> Now open Explore, and find the installation folder for your game.
> Right click once on the installation folder (not the .exe file for launching the game, the folder for the entire game).
> Hopefully you will see the in the shell menu, "Take Ownership"; there is a picture on the website of what it looks like.
> Left click once on that, and in a second or two you will get the success message. Now try to launch the game, no reboot is required.
You can delete the original install file if you wish; I usually save the installation files for these handy utilities for future use, but it's up to you.
Please let me know how it goes, I really like the Windows 7 version but I have never used the W10 version.