Every program on C: drive not working

So starting today my computer decided to start having problems and now i get error

"a device attached to the system is not functioning" for example 

So basically any program with the UAC shield icon isnt working now. How can I fix this? its affecting a lot of my programs and id really appreciate some help...

Let's start with the obvious. Is there anything attached via usb? If so, what happens when you disconnect it? If not, I suggest you post in the Am I Infected forum on this site.

start in safe mode.....can you run programs then?

Welcome to Bleeping Computer.

Did you change anything prior to this starting?

From the error messages it may be that your C: drive is dying.

I disagree about the error pointing to the hard drive, but let's wait for the OP to respond and we can go from there ;)

Nah i havent changed anything it just started doing this :/

and yes i tried to unplug some of the usb stuff to see if that was messing with it and that doesnt seem to be the case...

SOME of the "usb stuff"? Please unplug EVERYTHING and let's see what happens.

SOME of the "usb stuff"? Please unplug EVERYTHING and let's see what happens.

still nothing 

I suggest you post in the Am I Infected forum. Let's rule malware in or out.