In the past couple days on a network that I manage, I have found 6 randomly named files like this:
4D2E2CB03318 (that's the file name) and opening in notepad: is: 23B11F97807412DDFF13728E7FE767B3E5BB586E
2F52988EF008 (that's the file name) and opening in notepad: 325B16E574B7A6F5F2B7493D6323489CCC6BF46B
Dated from 1/12/2017 win 4 hours of each other and have the ownership of 6 different owners.
All machines are running McAfee Enterprise updated 1/12/2017 and Malwarebytes 1.8 Updated 2017.01.13.10 with Malwarebytes Anti-Exploit for Business 1.08.2.1045 at the time of discovery.
Recently migrated to Server 2012 from 2008 server. I've scanned the 6 systems full Malwarebytes, McAfee, and ADWCleaner and nothing, no threats, or PUP's or anything.
Also randomly checked 100+ files, of various types across folders these users would have access to as well as their computers and nothing all files open successfully.
Also checked known locations within the machines and registries and no signs of anything.