I have MS Office 2000 Professional SP3 installed on a Vista SP2 computer, and I am able to open/edit/save files created in MS Office 2007 and higher versions that use Open XML Formats (e.g., docx, .xlsx, etc.) because I installed the Office Compatibility Pack (available for download at https://www.microsoft.com/en-us/download/details.aspx?id=3 for XP and Vista). See the Microsoft support article How to open new file formats in earlier versions of Microsoft Office for more information. Here's a sample image from my Word 2000 SP3 showing that I have the ability to open files with the older .doc format (MS Office 2000 and 2003) as well as the newer .docx format (MS Office 2007 and higher):
Office 2000 Compatibility Pack docx.png 9.7KB
The bigger problem you might have is that Windows Updates can be incredibly slow these days on on Vista SP2 machines (see <here> for a possible workaround if you are affected these slow updates) and installing 9 years worth of updates to patch Microsoft Office 2000 to Service Pack 3 (SP3) could be difficult. Microsoft Office 2000 has also reached the end of extended support (i.e., it has not been patched for security vulnerabilities for several years) which makes using this old version of MS Office inherently risky.
32-bit Vista Home Premium SP2 * Firefox v50.1.0 * NIS v18.104.22.168 * MBAM v2.2.1
Edited by lmacri, 22 December 2016 - 04:51 PM.