My company uses IBM Lotus Notes for email, but because I would never wish that program on my worst enemy, I am using Microsoft Outlook with the Lotus DAMO software. For the first few months it had been working great and then I began experiencing a warning message claiming that Outlook could not find a connection to the server, but would resume syncing once the connection was established. This connection process has gotten progressively worse and takes anywhere from 30 minutes to several hours before Outlook is able to establish a connection. Out of curiosity, I began watching network traffic to see if there was anything I could detect. Sifting through the traffic, I discovered TCP incoming/outgoing traffic to 188.8.131.52. I did some research and found that this IP has been associated with malware and that the resolve host is Anubis Networks located in Portugal. The traffic seemed to be generated at the same time I would push the Send/Receive button in Outlook. I have added firewall rules to block any incoming/outgoing traffic from 184.108.40.206. I've loaded MBAM and completed scans with no results, I have loaded Hijack This and did not see anything unusual; I've run a few different rootkit scanners that came up empty as well.
I apologize for the long description. What can I do to determine if this is indeed something to be worried about. Thank you.