I've been running a myriad of anti-malware products on my HP/CompaQ CQ2014 with custom 64-bit Windows 7 Home Premium SP1, AMD E-300 Radeon 1.30GHz, 3.0GB RAM, 500GB HDD, and the (dinosaur) Juno offline e-mail app (a form of which I've been using since the late 90s)
A click-jacker with a crap-load of adservers on their side managed to pollute all of the browsers I have here (IE, FF and Chrome), plus the intrinsic IE8 or 9 inside the Juno app. I knew something was amiss when either the mouse pointer wouldn't change to a pointing hand or, in Juno's case, a mouseover on articles on their 'start' page didn't change color.
I've managed to extricate the CJ from everything except Juno, between the anti-malwares such as SAS and Malwarebytes (as I speak MSERT is giving the whole C drive the once-over), and plugging whatever URLs I spot for the CJ's results into restricted sites under internet options. The Juno issue persists, but only for brief periods starting and stopping. I can only guess that some extraneous file in the Juno folder apart from the program itself must contain the culprit's data, and have to wait to see if MSERT catches it and possibly have to reinstall Juno.
Anything else I need to do, during or after MSERT has finished?