What OS (Win XP/2000, etc) are you using? What type of anti-virus are you using and when was the last time you ran a scan? Have you performed any anti-spyware scans? If not, start here:Download and scan with the free F-Bot Cleaner Tool
1. Unzip (extract) the F-Bot utility from the ZIP archive. Read "How to create/extract a ZIP File in Win XP
" if unsure how to do this.
2. Run F-Bot.exe by either double-clicking on it or start from COMMAND.COM or CMD.EXE by typing: "F-Bot.exe
" at the command prompt and pressing 'Enter
3. Reboot the system.
If that does not help, then see Trend Micro's specific removal instructions here