No, it's an all or nothing deal. The clone will recreate the disk sector-by-sector on the destination disk
Everything is copied. If you're having errors, then the errors are copied also.
Also, when the system boots up on different hardware, Windows is usually able to compensate for this and use the correct drivers.
But too many changes may make a repair necessary (the only way to tell this is to try and see).
But you'll have the copy of the drive to work with.
You can copy data over by copying the Users folder.
This contains the vast majority of user data.
If you use any special programs, you might want to check where they store data (for example, QuickBooks stores it's data in the Public directory rather than your profile's directory - but they are both located in the Users folder)
You cannot copy programs. The main reason is that they scatter stuff all over the system, and the installers are customized to do different things depending on how the system is setup (so the settings might not be transferred).
There are programs that say they can do this, but I've never see one that worked reliably.
For an idea of how this works, try Install Monitor from Mirekusoft ( http://www.mirekusoft.com/ ) They have free and trial versions of the program.
Then install a program and see what Intall Monitor does when used to uninstall it - IMO it's amazing!!!
So, in summary:
- a clone copies everything
- you cannot copy programs, you have to reinstall them
- you can copy data over - and the vast majority of it is in the Users folder