Nowadays, of course by default you have your real-time multi-layered anti-virus, anti-malware and anti-exploit/anti-ransomware tools set to automatically scan your downloaded files for malware, as this is a security-wise imperative.
Moreover, it is equally important to scan your downloaded files on-demand for malware before using them, as this could further help eliminate malware; BTW I speak from experience.
I myself scan all the files that I am about to download with VirusTotals's Vtzilla browser add-on before actually downloading them, and afterwards with my AV/AM (EAM Pro) and MBAM Free. If the files are big however, I use Metascan Online.
There are several reputable online file analyzers & services as well as on-demand scanners out there, and hence my question is as follows: How do you scan your downloaded files on-demand for malware before using them?
Please specify which tools and methods you use!
Thank you very much in advance!