Over time, my Windows 7 Home Premium x86, on an HP Pavilion a6248xPC, has gotten worse. Random programs will open on their own; it takes minutes for FF to open, and navigating around the desktop, has become a pain. I try and practice safe browsing techniques. I do not download music, movies, or anything that appears to be suspicious. The only movies that I have watched on this system have been on either Netflix, or YouTube. I have already ran Avast, Adaware (after uninstalling Avast), ESET online scan, MBAM, JRT, Adwcleaner, Sophos Virus Removal Tool, and CCleaner. Also, I have tried a few of these while the system was running in safe mode. ESET online scanner, picked up a few threats, and MBAM was able to delete one threat, while in safe mode. I tried setting the system up in a clean boot environment, but that did not help very much. I ran Hard Disk Sentinel, and my HDD was reported to have perfect health. I run CCleaner about one, to two times a day, and try to run all of the scans, about twice a week. Would someone please be able to help me diagnose, and fix this problem? Thank you very much for your time, and have a great day.