This is not specifically a Windows 8 issue but I wasn't sure where to post this. I have been struggling with this for over a month now. Up until yesterday I thought I had fixed it, I "fixed it" for three days and now its back.
I first posted about my issues here: http://www.reddit.com/r/techsupport/comments/2xah2g/strange_keyboardmouse_issues_coming_from_an_it_guy/
And most recently posted about it here: http://www.reddit.com/r/techsupport/comments/2z4v14/computer_behaves_as_alt_key_is_being_held_down/
It looked like my computer was fixed for about 3-4 days and it just started happening again.
After a random amount of time (though often seems to happen after playing a game more predictably) my computer behaves as if the ALT key is being held down. I can't right click, I can't type, all links in the browser get downloaded instead of opened, the computer becomes essentially worthless. It took me a long time to figure out that what I think is happening is the "ALT" key is getting "stuck".
What I have tried:
The issues is NOT the keyboard. I even bought a new one to make sure.
SS of my Sticky Keys Settings: http://i.imgur.com/8L9g3We.png 
I have reset my Bios
I reinstalled windows, but I did it through the built in setting in Windows 8 to reset Windows and NOT keep files. Which I know isnt as good as a full format.
I have swapped USB ports.
PLEASE TELL ME SOMEONE KNOWS WHATS GOING ON