Hello, all, and thank you in advance for the assistance. I am currently working on a customer's Toshiba Satellite C55 running Windows 8. Upon initial review, it was obvious that the machine was badly infected with numerous junkware and adware. Per our standard operating procedures, I backed up relevant data and restarted the machine in safe mode. Junk programs were uninstalled via CCleaner, scanned using MBytes, made copies of registry and repaired using CCleaner, cleaned up HDD using CCleaner, and restarted to Windows 8 (regular). Up to this point, all programs are installed from a flash drive. Typically, upon restart from safe, we run ESET Online Scanner. However, I noticed immediately that Chrome was giving me the "Could not connect to proxy server" error. I checked setting in Chrome to find that the "Proxy" tab was grayed out. I opened Internet Options from control panel -> Advanced -> LAN settings to find, as I had assumed it would be, the Proxy button selected. I deselected the Proxy settings, re-selected Automatically Detect Settings, and clicked OK. Same error from Chrome. Checked LAN settings again to find Proxy checked. Following this, I ran ComboFix, to no avail. Basically, every time I deselect Proxy settings (and even when I delete all Advanced Proxy Settings fields), something is automatically selecting it again. I have a few days to complete this, so no big rush. I really appreciate the help.