I've got a computer here that belongs to a family member that was very infected with adware/spyware. Her husband, at my direction, cleaned it with Malwarebytes, Emsisoft and ADWCleaner. The computer now seems clean and runs well, but the Proxy Server box in Internet Options is ticked and has to be unticked, after every restart or it has no internet connection and the Proxy Server of 127.0.0.1:8000 is back.
Here's what I've done since I've had it.
Malwarebytes anti root kit
Junkware Removal Tool
Tweaking.com Windows Repair tool - (reset registry, service and file permissions, reset proxy, repair hosts file,remove policies set by infections),
Manually cleared the proxy registry settings.
Cleared all items from Startup
Removed all suspicious items with Hijack This
I've also installed Win Patrol, and it's finding a "run once" startup item on every boot and all it's got is a number, but nothing else can locate it.
I'm out of things to try, the computer runs fine except for the proxy being reset with every boot.
I'll only have the computer for another day, but I can continue the work via my FIL and remotely after that.