I had a propblem with a popup and in-browser advertising which was all labelled Coolisale Coupons. I started by uninstalling a program (can't remember its exact name but it was top of the list when I clicked for most recent), I reset IE back to the defaults, I went into Firefox extensions and removed a coupons extension, I went into Chrome and removed a similar extension. Then I downloaded and ran Adwcleaner and cleaned.
Next day I was working away and decided to open Chrome. The moment I clicked on anything I got popups and new windows and rubbish ....I checked Firefox and IE and they both seem ok. I re-checked the extensions - nothing is listed which would cause a problem. I ran Adwclearner again and I downloaded and ran HitmanPro. I then downloaded Malwarebytes and it found some tracking cookies it didn't like. So after re-starting my computer again I tested Chrome only to find that nothing has changed. I can't use Chrome at all - it just keeps opening up into casino pages and producing popups. These now seem to be titled "Ads by Online Browser Advertising".
What can I do now? I have Windows 8 64bit, Outpost Firewall Pro and Nod 32.