MalwareBytes' Anti-Malware + McAfee Antivirus is ok and there should not be any issues.
As for Ad-Aware and Spybot Search&Destroy...mvps.org
is no longer recommending Spybot S&D
(or Ad-Aware) due to poor testing results. See here
- (scroll down and read under Freeware Antispyware Products)
. Further, most people don't understand how to use Spybot's TeaTimer
and that feature can cause more problems than it's worth. TeaTimer monitors changes to certain critical keys in Windows registry
but does not indicate if the change is normal or a modification made by a malware infection. The user must have an understanding of the registry
and how TeaTimer works in order to make informed decisions
to allow or deny the detected changes. If you don't have understanding how a particular security tool works, then you probably should not be using it. Additionally, TeaTimer may conflict with other security tools which do a much better job of protecting your computer and in some cases it will even prevent disinfection
of malware by those tools.
To be fair, there are now new versions of Spybot such as Spybot 2 + AV (Home & Pro)
and Spybot 2 Free
but I have not used them, nor read any reviews as to how well they perform.
As for Ad-Aware.
What does the future hold for Ad-Aware?Lavasoft Controversies
Ad-Aware...have gone into a downhill spiral over the past five years and recently sold the company to Solaria... Majorgeeks stopped listing Ad-Aware as a “pick” some years ago as we watched the quality of the company slip over the years...it can’t stand up to the new generation of anti-spyware applications...
Also read Lavasoft Turning to the Dark Side?
written by a former volunteer (now a MVP) who provided support for Ad-Aware but no longer uses the program.
With that said, the newer version of Ad-Aware Pro Security 10.4 has earned Certificates & Awards from AV-Test
and did well in Virus Bulletin August 2013 Testing results
You may want to read: Supplementing your Anti-Virus Program with Anti-Malware Tools