Many thanks for the Quick reply and advise Quietman7. I did everything as you asked, but nothing cured the problem. (Though a couple more of the pesky things were found and removed).
I ran Hijack this afterwards, and found this line -
O20 - Winlogon Notify: winofa32 - C:\WINDOWS\SYSTEM32\winofa32.dll
Hijack this removed it and I renamed the .dll in safemode. Upon restarting my PC is remaining calm (and F-Prot is remaining quiet, which is the main thing)
It would seem that my troubles had something to do with that .dll file.
It's the first time as well that I've looked up a dll on the net and found no info about it. Possibly a new variant of an old nasty?
Anyway, thank you very much for all your help. If things return I will seek your advice immediatly :D
PS - Before fixing the problem whilst in Safemode I too had the same symptoms as the poor person in this thread - http://www.bleepingcomputer.com/forums/t/53682/ul-window-seek/
(Just thought I'd mention it in case it's a similar thing)
Edited by LuKeY, 26 May 2006 - 01:54 PM.