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In allot of Microsoft products, and ones based on that.
There is another use for the Wheel on your mouse.
If you hold down CTRL and use the Wheel you can either
in Word: Zoom from 10 - 500 in Intervals of 10
in Excel: Zoom from 10-100 in Intervals of 15
in Outlook: in a Mail Zooms Unknown
IrfanView: Zoom from 64X48 - 6336X4752 in Intervals of 64 (may Very with Pictures)
in IE: Change Text Size from Smallest to Largest
Also in IE, if you hold down Shift and use the mouse it is same as clicking back and forward or Backspace/Alt+Left arrow Key and Alt + Right arrow key
Not sure if any of these have been said before if so please feel free to delete mine.