Advertising popups sounds more like WinFixer. Since I'm new to the HJT forum, I'll give you some of my advice rather than the HJT stuff which I can't seem to find.
Download Atribune's VundoFix tool at: http://www.atribune.org/content/view/24/2/
and print out the instructions (recommended so you don't screw up on a step).
After the download is complete, boot into safe mode. If you're having trouble with that, download Bootsafe.exe from here: http://www.superadblocker.com/bootsafe.html
and reboot into safe mode minimal.
Follow Atribune's instructions on how to use the tool. If no traces of Winfixer are found then it's a different malware infection and you should post back here ASAP. (Post back even if it is Winfixer because VundoFix might no completely clean your machine.)