In a landmark decision today the Federal Aviation Administration issued a decision today stating that Personal Electronic Devices (PEDs) are safe for use at all times during flight, with limited exception.
Cellular devices must be placed in airplane mode for the duration of the flight due to continuing FCC regulation prohibiting cellular signal broadcasting while airborne.
While this change will not take place immediately due to differing implementations across airlines, it is expected that most devices will be cleared for use on major airlines by the end of 2013.
Press release here: http://www.faa.gov/news/press_releases/news_story.cfm?newsId=15254\
FAQ here: http://www.faa.gov/about/initiatives/ped/faq/