Decided to register and post this as I've been having an ongoing issue and it seems the help and support given here is top notch.
I'm no stranger to spyware/malware/virus infection and removal but this latest issue I'm having is a complete pain. It started with a random command prompt request when I wasn't doing anything that would require a command prompt, I felt it was suspicious when I hit the cancel button and the request kept popping up. I had to keep rapidly clicking cancel, but whilst attempting to click something else I ended up hitting 'ok', presumably infecting my system. I noticed that my Internet Explorer was frequently hanging and crashing after that; tellingly, every time I try to access any kind of website to do with spyware/malware/virus removal, Internet Explorer conveniently cannot load the page. More infuriatingly, I can't download anything, anything at all, from .jpegs to info files, to even patching an MMORPG. Downloads simply hang, or the downloader box just disappears midstream.
I've booted the computer into safe mode numerous times to try to fix the problem; I've run rkill, MBAM, SuperAntiSpyware, and even Combofix, but no success with any of those. SuperAntiSpyware reveals the same problem each time - it detects 3 'DisabledSecurityOptions' and a bunch of tracking cookies. Whilst SAS tells me it has successfully quarantined/deleted them, they show up again on the next scan. Related to the download problem above, I cannot update the database for SAS, as I get a 'download fail' message when attempting to update the definitions. MBAM reveals a Hijack and 3 other errors I've never heard of; again, though MBAM reports a successful quarantine/delete, they show up again in the next scan. Combofix, which usually blitzes my problems, doesn't seem to do anything at all. This is also the first time I've had to rename Combofix.exe as the program previously shutdown midway through the installer. Eset.com, which is also a reliable scanner I've used in the past can't update it's definition database to being scanning.
I'm at my wits end here, any help would be apreciated!