I've been working on this computer for a few days now, and am beyond my knowledge.
Viper Business (AV from Sunbelt) detected and removed what they called Trojan.Win32.Generic!BT. I have since updated and scanned with Malware Bytes and Spybot S&D, and updated Spyware Blaster. I have also ran TDSSKiller and Minitoolbox. Everything is coming up clean, except still seeing occasional tracking cookies.
I don't seem to be having any problems with any other programs except IE. Firefox runs fine. The PC had IE7 on it before this happened; in the course of trying to fix it I installed IE8. The installation seemed to go fine. When I go to start IE (both 7 and 8 are same here), the home page starts to load and I get an message saying 'IE is not your default browser, would you like to make it so' (or close to that, it is the standard default browser message I see all the time), and whether I click yes or no it just sits there spinning its wheels and eventually says 'Internet Explorer is not responding'. I can close it out with taskmanager, but then go to restart it again or even after a reboot, get the same thing.
Currently I only have a Remote Desktop Connection to this PC, so haven't been able to try this with a safeboot. I may be able to physically get to the PC this coming week, so I am trying to get everything set up for this if needed.
Thank you so much for any help you can give me.