working with vista homeprem sp2 32bit here. ran a quick avast scan a few minutes ago, it caught some small-time junk in the temporary internet files (which were purged easily enough), but it also pointed out C:\users\all users as "the system cannot find the path specified". so I open up windows explorer and try to go there. cue the "refers to a location that is unavailable" error message. now, I don't usually need to prod around in there so I'm not familiar with what normally happens, but I know vista loves to have a bunch of directories displayed that are shortcuts it uses for people who leave "hide protected OS files" checked (I don't, I want to see what's where) which really ought to not be shown when you're not hiding stuff but I digress, that's for MS to be groused at after win8 flops.
SO. should I panic that I've had another thing sneak past the security screens (mvp hosts file, spyware blaster, avast's shields, mbam scans)? nothing else seems out of sorts, but one man's paranoia is another man's preparation, and all.