Those who are trained in the use of ComboFix, know what it routinely does when instructing someone to run the tool. Other changes can be determined by analyzing the output of the log it generates.
As a general policy, Bleeping Computer does not offer advice
on how to run ComboFix unless we asked someone to run it or if there is a problem with the computer caused by running the tool. This is because people should not be using ComboFix without being advised to do so by a trained expert (see here
) who is assisting them deal with a malware problem.