A very obvious symptom is that the bar on top, which includes IE, recycle bin, etc. has disappeared. I also get the following error message when opening certain folders or directories or when saving files to particular directories (i.e. computer, network, several control panel windows, desktop, etc.)
C:\Windows\system32\config\systemprofile\Desktop refers to a location that is unavailable. It could be on a hard drive on this computer or on a network. Check to make sure that the disk is properly inserted or that you are connected to the internet or your network and then try again. If it still cannot be located, the information might have been moved to a different location.
The fonts have also changed on some of the components (i.e. display settings window, internet tabs, etc.) and appear to be pixelated.
Clicking on Documents, Pictures, and Music from the start menu doesn't open these windows. Clicking on the games from the star menu and double-clicking the application do not launch these games but they could be opened from the start > programs directory.