I suppose it depends on what is infecting you, of course. But there is much help to be found here at Bleeping Computer. Some options:
Depending on your level of expertise:
There is a forum here at Bleeping Computer for self help, you can find it HERE
Or, for help with removing your infection I would like to refer you to the Highjack This (HJT) forum here at BleepingComputer.com: First:
Read the Preparation Guide found HERE
. It is very important that you follow ALL of the instructions found within. (There are many important steps in this guide that may clean your computer.) Second:
Post your system information along with a brief description of the problems you are having, and your HJT log in the HJT forum found HERE
Please, after you post your HJT log DO NOT make another post in the HJT forum until it has been responded to by a member of the HJT Team. The first thing they look for, when looking for logs to reply to, is 0 replies. If you make another post there will be 1 reply. The team member glancing over the replies might think someone is already helping you out and will not respond. So, just make your post and let it sit there until a team member responds. The volunteers who work that forum are very busy, so please be patient and wait for a response. It can sometimes take a few days.
If, after finishing your work with the folks at the HJT forum you have issues with XP related to the removal of the infection, then come back in here and let us help you get your computer back to normal.
You are in good hands! Good luck!