Have you tried clearing the cache? If Chrome is acting sluggish for me, clearing the cache usually helps.
If not, try uninstalling Chrome and reinstalling an old version via OldApps.com
to see if it is the latest update that is causing the issue.
Note: the latest stable version as of today is 12.0.742.91 (the OldApps page is outdated by a few days). I would pick an 11.x version to test out.
If that doesn't work, try disabling extensions. It's possible an update to one of them is causing the browser to malfunction.