As a general rule
, using more than one anti-spyware program like Malwarebytes' Anti-Malware, SuperAntispyware, Windows Defender, Spybot S&D, Ad-Aware, Spyware Terminator, etc. will not conflict with each other or your anti-virus if using only one
of them for real-time protection and others as stand-alone scanners. In fact, doing so increases your protection coverage without
causing the same kind of conflicts or affecting the stability of your system that can occur when using more than one anti-virus. The overlap of protection from using different signature databases will aid in detection and removal of more threats when scanning your system for malware. However, competing tools may provide redundant alerts which can be annoying and/or confusing as a result of the overlap in protection.
If using multiple real-time resident shields (TeaTimer, Ad-Watch, MBAM Protection Module, Spyware Terminator Shields, etc.) together at the same time, there can be conflicts
when each application tries to compete for resources and exclusive rights to perform an action. They may identify the activity of each other as suspicious and produce alerts. Further, your anti-virus may detect suspicious activity while these programs are scanning (reading) files, especially if it uses a heuristic scanning
engine, regardless if they are running in real-time or on demand. The anti-virus may even detect as threats, any malware removed by these programs and placed into quarantined areas. This can lead to a repetitive cycle of endless alerts or false alarms that continually warn a threat has been found if the contents of the quarantine folder are not removed before beginning a new security scan. Generally these conflicts are more of an annoyance rather than the significant conflicts which occur when running two anti-virus programs in real time.