Virus/ worm keeps coming back

Hello,
I seem to have gotten some viruses-worms,trojans that I can't seem to get rid of. My internet pages started to redirect, mainly to various advertising sites and of course adult sites and fake virus scanners. I scanned with Microsoft security essentials and got rid of everything but it kept on happening so I got Malwarebytes and scanned again. It cames up I had win32.autorun.tmp so I got rid of it restarted and scanned again but it was there again. I tryed again but this time the scan was almost done and I got the BSOD which happens everytime now. I then tried Spybot S&D and it scans fully but can't get rid of all infections because some of the files are in use. My computer wont boot in safe mode. I have no idea how to fix this Please help.

I'm not trying to bump my post I promise but I just realised that I left out some crucial information in my original post. When I start up my computer Spyhunter pops up to say that my Hosts file has been changed and that I should restore it, which is what I do. Should I be doing that? Also whenever I run a virus scan I disable the other anti-virus progams that are installed to stop anything conflicting. I can't update windows, I get an error that says "Windows could not search for new updates an error occurred while checking for new updates for your computer. code 80072EFE" I hope this extra information helps. Merry Christmas everyone.

Hello,

Please follow the instructions in ==>This Guide<==. If you cannot complete a step, skip it and continue.

Once the proper logs are created, then make a NEW TOPIC and post it ==>HERE<== Please include a description of your computer issues and what you have done to resolve them.

If you can produce at least some of the logs, then please create the new topic and explain what happens when you try to create the log(s) that you couldn't get. If you cannot produce any of the logs, then still post the topic and explain that you followed the Prep. Guide, were unable to create the logs, and describe what happens when you try to create the logs.

Orange Blossom