Is this a Windows operating system?
If this is a Windows operating system, do both computers have product codes for the same operating system?
When this is installed on the other computer will this be replacing the operating system already installed on it?
If a hard drive is moved to a new computer, the registry entries and drivers for the mass storage controller hardware on the new motherboard are not installed in Windows for the new computer you may not be able to start Windows. This is because each chipset uses a different Plug-n-Play (PNP) ID to identify it. If you move your motherboard, your registry will have multiple PNP IDs (for the old hardware as well as the new hardware). If there are multiple entries in the registry, Windows cannot determine which hardware to initialize and therefore fails with a STOP error. I would have to assume that installing a mirrored operating system would present the same potential for this problem. I know of some who have done this and gotten away with it, and then there those that have been able to correct the problem with a repair installation of the operating system, and then there are those that have had to do a fresh installation. It's a craps shoot at best.
If these two motherboards aren't the same models, using the same drivers, you will need to install the different drivers.
Edited by dc3, 05 November 2010 - 10:36 AM.