The error message you posted...is a common one, usually (if not always) relates to a registry problem.Using ComboFix won't help you with such.
ComboFix is a ptent malware tool and should be run only at the request of someone experienced with malware resolutions who is going to direct you how to overcome your malware problem.
In the event that you feel the need to post your ComboFix log...please post it at the appropriate BC forum (not this one), after reading guidance for posting such, Preparation Guide, Before Using Malware Removal Tools and Requesting Help - http://www.bleepingcomputer.com/forums/topic34773.html
Upon following the procedures listed in the Preparation Guide, post your log at BC Virus, Trojan, Spyware, and Malware Removal Logs - http://www.bleepingcomputer.com/forums/forum22.html
.If you want to attempt to correct your registry problem...again, do not post any logs here...and take a look at Corrupted Registry, Config.sys Missing or Corrupt - http://support.microsoft.com/kb/307545.
Edited by hamluis, 09 October 2010 - 06:41 PM.