Hello and welcome to Bleepingcomputer.
You need to be careful when downloading drivers from unknown sources.
This is a major no-no and a good way to get a Trojan or virus, I can not stress this enough.
Here is a suggestion, go to Add and remove programs or if Vista and up go to control panel and programs and features.
While in programs and features look to the left side and click VIEW INSTALLED UPDATES (this is for Vista & Windows 7) Here you will most likely see the program you used for the mouse update.
Un-install it from there.
Most USB mouses will work on native windows USB drivers.
If your USB mouse has issues, try unplugging it from the USB port and replug it, or try a different USB port.
I would also do a scan with MalwareBytes to be sure the driver you downloaded is not malicious.
Malwarebytes Anti malware http://www.malwarebytes.org/
Download the FREE version, update and perform a FULL scan.
Edited by MrBruce1959, 12 September 2010 - 07:52 PM.