Posted 04 June 2010 - 04:40 PM
I've been having the same problem is GTA Vice City. I've found that if you go into options, controls and set it to standard the mouse works.......... eventually. It's funny you posted this, because I was just about to.
If you already have your controls set to standard, set it to classic and then switch back to standard. I find that when I can click my mouse in the options menu then the problem goes away........ for a while.