Problem originally was reported as no keyboard functions. Mouse worked but no keyboard. Keyboard functions fine in BIOS and safe mode. I'll skip all the troubleshooting there because it eventually lead me down the path of infection. But one key note is that a lot of necessary services(IE Computer Browser, Network Connections) are not running and will not start.
Started out with a malwarebytes scan in safe mode which resulted in only a couple of traces found and removed which didn't help the problem at all. They were minimal threats anyway. Sorry don't have the log from that as I didn't have any intentions initially of turning to help.
So that brings us to last night. Ran combofix which stated it found a rootkit and needed to reboot. After the reboot and the rest of the scan I was then able to start my services as normal. Rebooted to test for keyboard and still nothing. Booted back to safe mode and services are off again and can't be restarted so I'm obviously missing something.
I went ahead and ran a DDS and GMER scan per your site's request and am positing those logs along with my combofix log from last night.
Also of note I'm only able to function in safemode at the moment and have no internet access from the machine so online scanners are currently not an option. I can easily xfer tools and logs to the machine via flash drive though.
I believe I've covered all of the basics, if you need any further info or scans/logs please let me know and I'll gladly post.