As a general rule
, using more than one anti-spyware program like Malwarebytes' Anti-Malware, SuperAntispyware, Spybot S&D, Ad-Aware, etc will not conflict with each other or your anti-virus if using only one of them for real time protection and others as stand-alone scanners. In fact, doing so increases your protection coverage without
causing the same kind of conflicts or affecting the stability of your system that can occur when using more than one anti-virus. The overlap of protection from using different signature databases will aid in detection and removal of more threats when scanning your system for malware. However
, if using all their real-time resident shields
(TeaTimer, Ad-Watch, MBAM Protection Module, Spyware Terminator Shields, etc) together at the same time, there can be conflicts
when each application tries to compete for resources and exclusive rights to perform an action. Additionally, competing tools may even provide redundant alerts which can be annoying and/or confusing.
PC Tools are the makers of ThreatFire. Why do you not trust them?