Did you try doing everything mentioned in the Malwarebytes page located here
? Or you could also try this site
on how to get Malwarebytes to run successfully.
I would also look at the rkill instructions listed here
for several different ways you could try and run rkill.
I noticed that you said you were posting this from your desktop so I am assuming it's another computer that you are having problems with? Are you able to boot into safe mode with networking on the other computer using the F8 method listed here
You could always download the programs such as rkill, MBAM, and SAS to a flash drive on the good computer, and then then transfer them over to the infected computer starting with rkill, and then MBAM in normal mode if possisble.
Let me know if you have any questions.