Don't delete anything without being told to first as you may do more damage than good, post the log in the hjt section and somebody will help.
Try running the following from safe mode (Getting to safe-mode
you'll also need the virus template file from here
If your good with the command line also try Sophos Command Line scanner
Also try installing and running A2 Free
I'd also run Spybot
If your using Win2K/XP run adaware/spybot from "safe mode with command prompt"
At the C:\ prompt type the following:-
C:\progra~1\spybot~1\spybotsd.exe /autocheck /autofix