Hi and Welcome to BleepingComputer,
If you have already uninstalled the program there is no reason you cannot just delete those files. Many programs leave files behind after uinstallation and you can just delete those. If you do not need the space and are nervous about removing them, you can just leave them but if the program has been uninstalled, they are not doing anything and there is no need for them to be there.
Just so you know, it was just the Teatimer function in Spybot that was slowing your system down. I keep Spybot on my system but do not use the Teatimer function so Spybot is not running at all unless I open the program. When Teatimer is on, then it is running in the background at all times and that is what slows systems down.
SuperAntiSpyware is a better program for detection and removal of spyware and the free version does not run in the background, only on demand. If you leave the box checked for the icon to appear in the system tray it will appear it is running but it is not. I uncheck that box. I do not use the paid version because I do not see any need to have it run any way but on demand.
Edited by Stang777, 26 January 2010 - 05:15 PM.