Give us a little more information please. Were you actually able to run Malwarebytes? When was the last time you updated the definitions for both Malwarebytes and your McAfee? Do you have the Malwarebytes log? Are you able to get in to safe mode?
I would cut the internet conneciton first and then log in via safemode. Run Malwarebytes first and see if you can get SUPERAntiSpyware to install. If you can, run that as well. I realize that Malwarebytes isn't at its full effectiveness in safe mode but it can start the killing of startup processes and allow you to do more in the regular Windows mode. Keep in mind with SAS you will need to run it under each profile as it only scans the profile you are currently logged in to.
1. Get Malwarebytes HERE
2. Get SAS HERE
Edited by azfreetech, 31 October 2009 - 12:12 PM.