Hi, I am having a pecular problem. I am running XP Pro SP3, and everything is going along good, until I suddenly can't click on anything. The arrow moves, and the item reacts as if it has been clicked, but nothing happens. No menus, no actions. The only thing I have noticed is that when I run a certain application (RouteMatch TS --I work for a transit company) I get a "Run Time Error" before this happens. Sometimes there is not an error preceding it. I figured this was a problem with the RouteMatch software, because it has so many issues to begin with, but then It started happening on the Windows desktop as well. I consulted with my fellow IT person here, and neither of us has seen this before. I ran Malwarebytes, and it came up negative, no viruses according to Norton (not that it means much coming from Norton), and I disabled a few processes from starting with msconfig. Anyone have any other thoughts?