From www.aumha.org:0x000000E3: RESOURCE_NOT_OWNED
Various failures involving the NTFS file system
cause this condition.
I would suspect that malware should not be ruled out as a possible contributor, it's hard for me to say.
You could try running the chkdsk /r command, although I would not expect much.
How to use CHKDSK in the XP Recovery Console - http://pirules3.14.googlepages.com/recovery_console_chkdsk
IME, NTFS failures cannot be repaired, although there are tools which purport to be able to do such.
In my view, an NTFS problem is a bit worse than a hard drive problem. For one thing, the errors/situations are not readily pinpointed by any software I' have come across, whereas hard drive problems can be pinpointed even down to a specific sector of the drive, if the user has patience enough to do such.
My personal solution for dealing with NTFS problems...is to save whatever data I want from that partition, then do a clean install of the O/S. Such resolution holds no terror/regret for me because I have backups made and I maintain a copy of every program that I've used recently (within last 2 years) for future installations/repairs.
I suggest running the chkdsk /r command and then seeing what the results might be.