I have dell vostro 1500 running with Vista Ultimate. On Friday , my brother download a file called working generator.exe for one of his games. And thats it, after that my computer is never been same. First all the .exe files were non reponsive and wont start, would give a debugger error[97] ( its file is called desote.exe).

I downloaded OTM and moved the files, and then removed the entires from the registry using REGEDIT.
and then went to run MalwareBytes antimalware. It will open up the windows starts for 9 seconds and then the window closes, if i try to re-open, its gives an error saying
"Windows cannot access the specified device, path or file. you may not have the appropriate permission to access them"
Same is the case for HIJACK THIS, Sybot Search and Destory, and RootRepeal and same with COMBOFIX
in case of RootRePeal , i am getting the following error as soon as i start RootRepeal.exe
"FOPS - DeviceIoControl Error! Error Code = 0x00000024 Extended Info (0x000000f8)
DeviceIoControl Error! Errorr Code = 0x1e7"
if i select reports tab and try to check the options like drives, files etc and select scan, it gives an cannot initialize error also for RootRepeal.exe
can someone please help me, i cannot loose all the information i have on my laptop. Please i am desparate

Thanks and i Appreciate it.