Two methods, 1st one involves editing the registry, so again, back it up;
2nd method, which is the easiest and safest.
Control Panel/System and Security/Administrative Tools, click on Create and format hard disk partitions, right click the drive you want to hide and remove the drive letter. This will hide the drive in "My Computer"
To show the drive, just add the drive letter back.
Note: You cannot change/remove a drive letter to a volume that contains System, Boot or Page File.
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Edited by Adamsappleone, 11 May 2009 - 05:23 PM.