Do you have a tape backup of your server, including System State?
I had a similar problem after running combofix on a Windows 2000 Server configured as a DC. I could log onto the server as Administrator, but DNS and AD reported errors and wouldn't open.
The fix for my situation was to do the following:
- Reboot and press F8 when booting to get Safe Mode boot options
- Select "Directory Services Restore Mode"
- In Windows (Safe Mode), I used my tape backup software (BackeupExec 8) to restore the System State (including registry)
- I did this restore from a good backup from a date before I ran combofix
My backup software (BackupExec) wouldn't work initially in Safe Mode. In Safe Mode, I had to go to Services and open properties on each BackupExec service. In properties, I had to click the Logon tab and select "Use Local System Account" and then manually start these services to get my backup software to run in Safe Mode.
After the system state was restored, I rebooted the Win2000 server in normal mode and Active Directory and DNS work working again.
Here is Microsoft's direcctions on restoring the system state. These instructions use the Windows built-in backup software. When in Safe Mode, use your own backup software to do the system state restore (step 6 in the restore directions on the following page).http://support.microsoft.com/kb/240363
At least this worked for my situation.