I know this is an old post but I found it via a google search - I was having the same problem with these two mystery files.
Delete both files and modify the properties of the newly created (auto) files as read-only. Solved the problem for me.
I have no idea what they are - if they're a virus or spyware or something weird in Vista. I came across another forum where someone had these files, noticed they were HUGE and eating up all his disk space (same problem I was having), deleted them and modified the properties to read-only.
---edited to add---
These files appear to be part of Elite Keylogger - so, yeah, definitely spyware.
Edited by zentropy, 03 March 2009 - 02:46 PM.