Ok, you had some type of spyware that needed that file to load the spyware. Now that the spyware is gone it can't find the file to load and slow down your computer. So here is what I want you to do, so I can tell what is loading on your start-up.
and then extract it to a folder on your hard drive (do not extract it to your desktop, preferrably c:\hjt\) then double click on the .exe file and open it up. Once you load the program click "Do a system scan and save a logfile."
Then once it done doing a scan and it loads the NotePad of the results. Copy and paste the results in the HiJackThis