It is wise to have a good selection of anti malware products, but the more you have the slower the system will be.
That isn't a complete statement. Your system is really only going to be slowed down if you're running the real-time protection of the programs. (Particularly using more than one which isn't really recommended.) From taking a look at your topic in malware removal, I can see you mean SuperAntiSpyware, not SuperSpyware (which would be bad). Anyway, all three of the programs you listed require either using a time-limited trial or else payment for the full version to obtain real-time protection. So, unless you paid for one of them or are using the trial, you won't have real-time protection from them. Also, Ad-Aware is probably not necessary since you have Malwarebytes' Antimalware along with SuperAntiSpyware.
I would echo kahdah's suggestions and reinforce the idea of installing something like SpywareBlaster
if you haven't done so already. As for the anti-virus, remember this is protecting you from and detecting things that the other programs won't. So, while getting rid of McAfee especially since it is outdated is a wise choice, you will definitely want to replace it with something else. We do have a list of Freeware Replacements For Common Commercial Apps
that will give you a selection of programs to choose from, should you decide to go the freeware route.
If you want to go with a paid product, NOD32 (Eset)
, and Kaspersky
are typical recommendations. Usually, paid products will have free trials and it's a good idea to use them so you can see what you like and works well with your system. Hope that helps.