After trawling through everyone else's problems I think I have finally sorted out my hubbie's computer by following the advice given by you clever chaps! All I would like to know is, is the computer free from everything now as it is his business computer. I have run SmitFraudFix, mbam, ATF cleaner, Avast, SpyDoctor (which I must add didn't find any of the problems which worries me a bit as I have just paid for it!) and finally HijackThis to send to you.
If it helps the original problem was XP Antivirus 2008, Error Cleaner, Privacy Protector, Spyware&Malware Protection and browser hijacking which was most annoying. Whilst trying to clear this the software found Vundo and Trojan.Fake Alert.
Would appreciate your assistance.