Thank you for the replies - I had tried the specified approach previously with no luck - Vundofix didn't spot what was there unfortunately.
That having been said I can report a sucess.
I ran Kaspersky and scanned memory which revealed 49 processes with crocked .dll files.
The files were
and were riddled through and being used by practically every process running as far as I can see. Obviously this meant that I couldn't just kill them off so I rebooted in safe mode with command prompt, shifted to C:\Windows\system32 and renamed the files to
then I ran SpyBot S&D again and killed the offending three registry items, rescanned to confirm then rebooted.
On rebooting into normal mode I ran Spybot one last time to confirm and bingo no more Virtumonde.
One slightly worrying issue is that some process reported that the .dll files were absent in a dialogue box as I started windows. The process didn't identify itself but everything seems to be working at the moment so I'll probably next check up on what those two files actually were next to confirm that I haven't crippled something in the process.
Windows start up is still a little slow for me now but I suspect that this is to do with programmes that technically I do need but not actually on start up - Such as InCD (for DvD writing) from Nero I think although I can't specifically remember installing it and so I'll prune them off if I can.
Initial crisis is over though as my wife can get onto eBay again now.
Thanks for your replies again, hope the issue has helped others a little bit too.