You can do anything you want with your system...
If you are asking whether it's wise to disable a fundamental utility of XP/Windows, I would have to suggest that "No!" would be an honest answer.
Perhaps you don't really understand what chkdsk is/does, etc. In that case, you might gain by reading Chkdsk Explained, Understanding What Chkdsk Does - http://support.microsoft.com/kb/314835/EN-US/
If chkdsk takes an inordinate amount of time...to complete its functions...it's either because the disk has been damaged in some way or is deteriorating...or proper maintenance has not been performed in some time.http://searchwincomputing.techtarget.com/t...1263963,00.html
But you are the captain of your ship